Human TGFBR2 ELISA Kit
KOA0781
1 Kit
ELISA
Human
15.6 pg/ml - 1000 pg/ml
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Product Details
Human TGFBR2 AccuSignal ELISA Kit - KOA0781
AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TbetaR-II, TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbeta RII, Tgfbr2, TGFR 2, TGFR-2, TGFR2_HUMAN, Transforming growth factor beta receptor II (70/80kDa), Transforming growth factor-beta receptor type II
ELISA Kit
15.6 pg/ml - 1000 pg/ml
Target Details
TGFBR2 - View All TGFBR2 Products
Human
Expression system for standard: NSO; Immunogen sequence: I24-D159
Natural and recombinant human TGFBR2. There is no detectable cross-reactivity with other relevant proteins.
P37173 - UniProtKB
NP_001020018.1 - NCBI Protein
Application Details
ELISA
Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml, 15.6pg/ml human TGFBR2 standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human TGFBR2 standard solution and each sample be measured in duplicate.
Formulation
Heparin Sodium
Shipping & Handling
Wet Ice
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
See kit insert for complete instructions.
TGFBR2(transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been cha...
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